A 24‑year‑old male Solomon Island eclectus parrot with a testicular round‑cell tumor was treated with hormone drugs (tamoxifen, leuprolide, deslorelin) and carboplatin chemo before surgery, leading to a 95% shrinkage and successful removal with no recurrence after seven months. This is the first report of such a treatment in a bird, but it doesn’t directly apply to human health‑hacking or typical biohacker goals.

An intracoelomic mass was palpated on an annual exam of a 24-year-old male Solomon Island eclectus parrot (<i>Eclectus roratus solomonensis</i>). The initial diagnostic workup included a complete blood count, plasma biochemistry panel, and coelomic ultrasound. Computed tomography was highly suggestive of a testicular mass. Tamoxifen and the gonadotropin-releasing hormone agonists leuprolide and deslorelin were administered as neoadjunctive endocrine therapies. Biopsy and histologic examination confirmed a testicular mass consistent with a round cell tumor. Four doses of carboplatin 15 mg/kg IV were administered as neoadjunctive chemotherapy, and testicular size decreased by approximately 95%. The remaining gross tumor was removed via orchidectomy with clean but narrow margins. Seven months following surgery, a contrast CT scan did not show any evidence of recurrence of or metastasis from the original mass. This is the first report of successful treatment of a testicular tumor in a psittacine with neoadjuvant chemotherapy and orchidectomy.