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AEDP, Ala-Glu-Asp-Pro, Cortex Tetrapeptide
A synthetic tetrapeptide bioregulator that targets the brain to promote neuroprotection, reduce inflammation, and enhance cognitive function.
| Route | |
|---|---|
|
Subcutaneous (SC)
10 mcg/kg
|
|
|
Intranasal
0.1-1 mg
|
How It Works: Cortagen acts as a bioregulator by influencing gene expression in brain tissues, promoting neuroprotection and cognitive enhancement.
Zarubina. I V IV; Shabanov. P D PD
In rats, a brain‑specific protein mix called cortagen helped protect the brain from damage caused by repeated low‑oxygen events. It lowered the severity of neurological problems, improved the animals' normal behavior, and acted as an antioxidant during both early and later stages of the damage process.
Kozina. L S LS
A study in rats found that giving the peptide cortagen (along with another peptide, epithalon) lowered markers of oxidative damage in the brain and blood, but it also reduced the natural antioxidant activity in those tissues. The work was done in animals using injections, so it doesn't directly tell us how to use cortagen in people.
Gumen. A V AV; Kozinets. I A IA; Shanin. S N SN; Malinin. V V VV; Rybakina. E G...
In mice, older animals' immune cells make less of a signal that helps T‑cells work, and three short synthetic peptides (Vilon, Epithalon, Cortagen) change this signal differently in young versus old mice. This hints that such peptides might tweak age‑related immune decline, but the work is early and done only in mouse cells.