Score
2
2007
pubmed
4 citations
Effects of bioactive tetrapeptides on free-radical processes.
Kozina. L S LS
Key Findings
- Injecting cortagen into rats decreased levels of lipid peroxidation products.
- Cortagen reduced oxidative modifications of proteins in rat serum and brain.
- The same treatment also suppressed the overall antioxidant activity in those tissues.
Practical Outcomes
- The results hint that cortagen might have antioxidant‑like effects, but the accompanying drop in natural antioxidant activity raises questions. For biohackers, the study offers limited, indirect evidence and does not provide a clear dosing or safety guideline for human use. More human research is needed before it can be turned into a practical protocol.
Summary
A study in rats found that giving the peptide cortagen (along with another peptide, epithalon) lowered markers of oxidative damage in the brain and blood, but it also reduced the natural antioxidant activity in those tissues. The work was done in animals using injections, so it doesn't directly tell us how to use cortagen in people.
Abstract
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
Study Information
Provider
pubmed
Year
2007
Date
2007-06-01T00:00:00.000Z
DOI
10.1007/s10517-007-0230-8
Citations
4
References
10