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Cortagen

AEDP, Ala-Glu-Asp-Pro, Cortex Tetrapeptide

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Studies 14
Trials 43
Unknown OBSERVATIONAL NCT05219214

China Rheumatoid Arthritis Registry of Patients With Chinese Medicine

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

A multi-center registration study of clinical characteristics of rheumatoid arthritis (RA) patients with Chinese medicine.

Interventions

Name: Chinese medicine
Type: OTHER
Description: There are no restrictions on TCM therapy, including Chinese herbal medicine, Chinese patent medicine, external treatment, acupuncture and moxibustion, etc

Primary Outcomes

Measure: Percentage of Participants Who Achieved Disease Activity Score for 28 Different Joints With C-reactive Protein Value (DAS28{CRP}) Remission (DAS28 <2.6) at Month 12
TimeFrame: Month 12
Description: DAS28 is a modification of the original DAS and is based on a count of 28 swollen and tender joints and is used to evaluate a participant's response to treatment. DAS 28 CRP utilizing joint scores from the following 28 joints: elbows, shoulders, elbow, wrists, metacarpal- phalangeal I-V, proximal interphalangeal I-V and knees and is calculated using the following formula: DAS28 (CRP) = 0.56\*√(TJC28) +0.28\*√(SJC28)+0.014\*GH+0.36\*ln(CRP+1)+0.96. Where TJC - Tender joint Count, SJC= Swollen Joint Count, (GH=participant assessment of disease activity using a 100 millimeter \[mm\] visual analogue scale with 0 = best, 100 = worst) and CRP= C reactive Protein (in \[milligrams/liter\] mg/L). It ranges between 0.96 and 8.61. High score (worse outcome) and low scores (better outcome).

Trial Information

NCT ID

NCT05219214

Status

Unknown

Study Type

OBSERVATIONAL

Sponsor

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Last Updated

December 15, 2025