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Follistatin 315

Activin-Binding Protein, FSH-Suppressing Protein, FST-315, FS-315

Quick Stats
Studies 14
Trials 93
Completed NA INTERVENTIONAL NCT04381390

Egg Consumption and Muscular Adaptations

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality. The investigators hypothesis is that whole eggs would create a greater improvement in skeletal regulatory markers, hormonal responses and body composition than egg white ingestion in resistance-trained men.

Detailed Description

The aim of this investigation was to compare the effects of whole egg versus egg white ingestion (daily and after training sessions) during 12 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to: To investigate the extent to which both whole egg and egg white ingestion will improve anabolic factors, fat free mass, fat mass and decrease catabolic markers after 12 weeks of resistance training in resistance-trained men.

Interventions

Name: Whole egg and resistance training
Type: DIETARY_SUPPLEMENT
Description: This intervention consisted of whole egg consumption concomitant with 12 weeks of resistance training. Subject ingested three whole eggs per day immediately after resistance training.
Name: Egg whites and resistance training
Type: DIETARY_SUPPLEMENT
Description: This intervention consisted of egg white consumption concomitant with 12 weeks of resistance training. Subject ingested an isonitrogenous quantity of six egg whites per day immediately after resistance training.

Primary Outcomes

Measure: Circulatory Myokines levels
TimeFrame: 12 weeks
Description: Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentration of myostatin, follistatin, FGF-2, TGF-β1 and ACVA.
Measure: Circulatory hormone levels
TimeFrame: 12 weeks
Description: Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentrations of testosterone, IGF-1, insulin and cortisol
Measure: Muscle mass
TimeFrame: 12 weeks
Description: Skeletal muscle mass will be evaluated using computed tomography
Measure: Body fatness
TimeFrame: 12 weeks
Description: Body fat will be evaluated using bioelectrical impedance

Trial Information

NCT ID

NCT04381390

Status

Completed

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

Alexei Wong

Last Updated

December 15, 2025

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