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Follistatin 315

Activin-Binding Protein, FSH-Suppressing Protein, FST-315, FS-315

Quick Stats
Studies 14
Trials 93
Completed NA INTERVENTIONAL NCT04509297

Resistance Training and Milk Supplementation

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

Post-resistance training high protein milk supplementation may be a viable method to elicit muscular gains. The investigators hypothesis is that high protein milk supplementation would improve skeletal regulatory markers, hormonal responses and body composition in resistance-trained men.

Detailed Description

The aim of this investigation was to compare the effects of high protein milk supplementation (daily and after training sessions) during 6 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to: To investigate the extent to which high protein milk supplementation will improve anabolic factors, lean body mass, fat mass and decrease catabolic markers after 6 weeks of resistance training in resistance-trained men.

Interventions

Name: high protein milk
Type: DIETARY_SUPPLEMENT
Description: This intervention consisted of high protein milk consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.
Name: Placebo
Type: DIETARY_SUPPLEMENT
Description: This intervention consisted of the consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

Primary Outcomes

Measure: Circulatory Myokines levels
TimeFrame: 6 weeks
Description: Fasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentration of myostatin and follistatin.
Measure: Circulatory hormone levels
TimeFrame: 6 weeks
Description: Fasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentrations of testosterone, IGF-1, growth hormone, insulin and cortisol
Measure: Body composition
TimeFrame: 6 weeks
Description: Lean body mass and body fatness will be evaluated using bioelectrical impedance

Trial Information

NCT ID

NCT04509297

Status

Completed

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

Marymount University

Last Updated

December 15, 2025

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