Follistatin 315
Activin-Binding Protein, FSH-Suppressing Protein, FST-315, FS-315
Not Yet Recruiting
NA
INTERVENTIONAL
NCT07189624
Effect of Acute Endurance Exercise on the Production of FGF21 and Follistatin in Patients With Hepatocellular Carcinoma
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
The main purpose of the study is to characterize the production of hepatokines (FGF21 and Follistatin) in response to a submaximal exercise on an ergocycle, in patients with hepatocellular carcinoma. The effect of exercise on hepatokines and metabolites production in liver cancer patients is not known. Studying this production could help to provide relevant recommendations for training programming in these patients.
Interventions
Name:
Exercise
Type:
OTHER
Description:
30-minutes exercise on a bicycle with heart rate monitor and gas exchange analyzer.
Primary Outcomes
Measure:
Systemic hepatokines rates (FGF-21 and follistatin)
TimeFrame:
Baseline (pre-exercise), immediately after exercise, 1 hour after the end of exercise
Description:
Blood samples
Trial Information
NCT ID
NCT07189624
Status
Not Yet Recruiting
Study Type
INTERVENTIONAL
Phases
NA
Sponsor
University Hospital, Clermont-Ferrand
Last Updated
December 15, 2025