Completed
NA
INTERVENTIONAL
NCT00742235
hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
Vitamin D deficiency (low levels of vitamin D in the blood) is a common problem. A recently discovered protein, called hCAP18, likely plays an important role in the immune system and may depend on adequate levels of vitamin D. It is not known what levels of vitamin D are needed to allow the body to make this protein. Nor is it known if giving vitamin D to people who are found to be deficient will help boost levels of hCAP18. This study aims to clarify the relationship between vitamin D levels and hCAP18.
Interventions
Name:
ergocalciferol
Type:
DRUG
Description:
Ergocalciferol 50,000 IU given every other day for 5 total doses
Primary Outcomes
Measure:
hCAP18 Levels
TimeFrame:
Baseline
Description:
Measure:
Baseline 25-OH Vitamin D Level
TimeFrame:
Baseline
Description:
Trial Information
NCT ID
NCT00742235
Status
Completed
Study Type
INTERVENTIONAL
Phases
NA
Sponsor
Massachusetts General Hospital
Last Updated
December 15, 2025