Completed
NA
INTERVENTIONAL
NCT02930434
Effects of Antarctic Environment on Vitamin D Status and Health Risk Biomarkers of Its Inhabitants
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
The purpose of this study is to evaluate vitamin D (VD) deficiency in the population of Chilean Antarctica and evaluate the efficacy and safety of VD supplementation to decrease VD deficiency and favorably influence biomarkers for bone, cardiovascular, and immune health risk in the inhabitants of Chilean Antarctica.
Detailed Description
The present study consists of an initial cross-sectional evaluation of VD status and specific health biomarkers in inhabitants of Chilean Antarctica, followed by a randomized controlled trial evaluating two acceptable approaches of vitamin D supplementation (cholecalciferol 600 IU daily vs. 25000 IU weekly) in Antarctic inhabitants.
Interventions
Name:
cholecalciferol
Type:
DIETARY_SUPPLEMENT
Description:
Administration of vitamin D3
Primary Outcomes
Measure:
Change in serum 25-hydroxyvitamin D concentration
TimeFrame:
at end of Antarctic residency or 1 year (90-365 days), whichever came first
Description:
In Antarctic inhabitants not supplemented with VD that exit Antarctica before start of RCT phase of study.
Trial Information
NCT ID
NCT02930434
Status
Completed
Study Type
INTERVENTIONAL
Phases
NA
Sponsor
Pontificia Universidad Catolica de Chile
Last Updated
December 15, 2025