Dietary Diversities: Exploring the Influence of Keto Diet and Intermittent Fasting on Oral Health and Salivary Inflammatory Biomarkers
Brief Summary
This study aims to investigate the impact of short term, two distinct dietary interventions, namely the Keto diet and Intermittent Fasting on oral health by measuring the severity of: * Periodontal diseases (Gingivitis). * Oral health status (Plaque index). As well as measuring the impact of these different dietary pattern on the levels of C- Reactive Protein, IL-6, TNF-a in mean of inflammatory biomarkers as well as LL- 37 peptide as well as measuring salivary flow and ph. Objectives of the study 1. Evaluate the impact of Keto diet and Intermittent Fasting on oral health among the Iraqi population. 2. Assess changes in inflammatory biomarkers within the study groups before and after the intervention period. 3. Compare the effects of Keto diet and Intermittent Fasting on oral health and inflammatory biomarkers between the two intervention groups. 4. Examine the variations in oral health and inflammatory biomarkers within each group by comparing the baseline (Iraqi diet) and post-intervention stages. 5. Investigate the influence of Keto diet and Intermittent Fasting on the levels of LL37, an antimicrobial peptide.
Interventions
Primary Outcomes
Trial Information
NCT06597708
Completed
INTERVENTIONAL
EARLY PHASE1
Al-Mustansiriyah University
December 15, 2025