Menu
Peptide Database
Results
No peptides found
Featured

Use search to browse all 100+ peptides

LL-37

Cathelicidin, hCAP-18, FALL-39, CAP-18

Quick Stats
Studies 2230
Trials 95
Completed NA INTERVENTIONAL NCT01835639

Vitamin D Supplementation in Glomerular Disease

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

This multi-site, pilot study will assess vitamin D supplementation in children and young adults with Glomerular Disease. .

Detailed Description

Vitamin D deficiency has been linked to a variety of adverse health outcomes. Nephrotic patients have very low vitamin D levels, and the underlying mechanisms are not known. Furthermore, approaches to safely and effectively supplement vitamin D in these patients have not been established. The purpose of this research study is to learn if vitamin D supplementation is safe and effective in patients with primary glomerular disease and to also help establish the treatment guidelines. About 35 patients with primary glomerular disease, ages 5-30 years old, will take part in this study. Participants will be asked to take vitamin D supplements each day for 12 weeks and will have 3 study visits.

Interventions

Name: Cholecalciferol, 2000 or 4000 IUs by mouth daily for 12 weeks
Type: DIETARY_SUPPLEMENT
Description: Supplements will be provided as oral capsules.

Primary Outcomes

Measure: To assess the efficacy of vitamin D supplementation, by the increase in total and free 25(OH)D levels.
TimeFrame: 12 weeks
Description:
Measure: To assess the safety of vitamin D supplementation, by serum Ionized calcium (ICal), Pi, and 25(OH)D, and urinary calcium excretion.
TimeFrame: 12 weeks
Description:

Trial Information

NCT ID

NCT01835639

Status

Completed

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

Children's Hospital of Philadelphia

Last Updated

December 15, 2025