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Melanotan-I

Afamelanotide, MT-I, [Nle4-D-Phe7]-α-MSH, Scenesse, CUV-1647

A synthetic analog of alpha-melanocyte-stimulating hormone that stimulates melanogenesis, increasing skin pigmentation and providing photoprotection against UV radiation.

Quick Stats
Studies 225
Trials 100
Formula C78H111N21O19
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Completed NCT01431326

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Daniel Benjamin
OBSERVATIONAL
Updated Dec 15, 2025
Completed PHASE4 NCT00346216

Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE3 NCT03793166

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

National Cancer Institute (NCI)
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT00490139

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

Novartis Pharmaceuticals
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE3 NCT01274338

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

National Cancer Institute (NCI)
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT05099640

A Study of PTC923 in Participants With Phenylketonuria

PTC Therapeutics
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT03595553

Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection

Summit Therapeutics
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT00617032

Phase 1 Dose Escalation Study of Intra-Articular Administration of tgAAC94

Targeted Genetics Corporation
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT02466555

Music Therapy in Sickle Cell Transition Study

University Hospitals Cleveland Medical Center
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT05159778

Phase 2 Study of Imprime PGG and Pembrolizumab in Patients With HR+/HER2- Metastatic Breast Cancer (mBCA)

HiberCell, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT00006734

Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor

Children's Oncology Group
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NA NCT07017998

External Therapy for Tinnitus Management

Restorear Devices LLC
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT03237234

Enhancing Corticospinal Activation for Improved Walking Function

Shepherd Center, Atlanta GA
INTERVENTIONAL
Updated Dec 15, 2025