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Melanotan-I

Afamelanotide, MT-I, [Nle4-D-Phe7]-α-MSH, Scenesse, CUV-1647

A synthetic analog of alpha-melanocyte-stimulating hormone that stimulates melanogenesis, increasing skin pigmentation and providing photoprotection against UV radiation.

Quick Stats
Studies 225
Trials 100
Formula C78H111N21O19
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Completed PHASE2 NCT05546476

Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15

Pfizer
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1, PHASE2 NCT00924352

Trial of Dasatinib Plus Ixabepilone in 2nd or 3rd Line Metastatic Breast Cancer

Accelerated Community Oncology Research Network
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1, PHASE2 NCT00731731

Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

National Cancer Institute (NCI)
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT00820872

Docetaxel, Carboplatin, Trastuzumab, and Lapatinib in Treating Patients With Early Stage Breast Cancer

Alliance for Clinical Trials in Oncology
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT06937931

A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults

Ipsen
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE1 NCT03228537

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

National Cancer Institute (NCI)
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT05586971

Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients

LG Chem
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT03175367

Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia

Regeneron Pharmaceuticals
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT05112601

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

National Cancer Institute (NCI)
INTERVENTIONAL
Updated Dec 15, 2025
Suspended PHASE3 NCT03811015

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

National Cancer Institute (NCI)
INTERVENTIONAL
Updated Dec 15, 2025
Terminated PHASE3 NCT03839940

Dexamethasone in Reducing Everolimus-Induced Oral Stomatitis in Patients With Cancer

Alliance for Clinical Trials in Oncology
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1, PHASE2 NCT00325416

Study of Melphalan and Topotecan (MT) Followed by Autologous Stem Cell Rescue in Patients With Multiple Myeloma.

H. Lee Moffitt Cancer Center and Research Institute
INTERVENTIONAL
Updated Dec 15, 2025
Unknown PHASE2, PHASE3 NCT02065687

Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

Gynecologic Oncology Group
INTERVENTIONAL
Updated Dec 15, 2025