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Melanostatine-5, White 05

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Studies 4
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Recruiting OBSERVATIONAL NCT05411341

Comparison of Two Different Optical Biometric Systems

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

Primary objective of this study is to evaluate and compare the measurements of two different optical biometrics systems in patients who will undergo cataract surgery or presbyopia surgery using intraocular lenses (IOL-PC).

Detailed Description

This is a prospective study including patients visiting the outpatient Ophthalmology clinic of the University General Hospital of Alexandroupolis, who suffer from diagnosed cataract or presbyopia and are going to undergo implantation of intraocular lenses surgery. The patients will be fully informed about the procedure and the purpose of the study and a written informed consent will be provided by all participants. They will then undergo an ocular biometry examination using two optical biometric systems, Argos (Alcon Laboratories, Inc.) and IOLMaster 500 (Carl Zeiss Meditec AG). IOL Master 500 (Carl Zeiss Meditec AG) is a non-invasive optical biometer that uses partial coherence interferometry (PCI) with a wavelength of 780 nm to measure the AL of the eye. Argos (Alcon Laboratories, Inc.) is a novel non-invasive optical biometer that uses swept source optical coherence tomography (SS-OCT) with a wavelength of 1050 nm. The measurements of the two systems that will be compared are the axial length, the keratometry values, the anterior chamber depth (ACD), the horizontal corneal diameter (white to white \[WTW\]) and the lens power in diopters (D).

Interventions

Name: Argos (Alcon Laboratories, Inc.)
Type: DEVICE
Description: An ocular biometry examination will be performed on the affected eyes using the Argos device.
Name: IOLMaster 500 (Carl Zeiss Meditec AG)
Type: DEVICE
Description: An ocular biometry examination will be performed on the affected eyes using the IOL Master 500 device.

Primary Outcomes

Measure: Axial length
TimeFrame: 1 week
Description: The measurement of the axial length of the affected eye using both devices
Measure: Keratometry values
TimeFrame: 1 week
Description: The measurement of keratometry values K1: flat meridian of the anterior corneal surface and K2: steep meridian of the anterior corneal surface of the affected eye using both devices.
Measure: Lens power (D)
TimeFrame: 1 week
Description: The power of the lens is calculated by each device as a function of biometric measurements

Trial Information

NCT ID

NCT05411341

Status

Recruiting

Study Type

OBSERVATIONAL

Sponsor

Democritus University of Thrace

Last Updated

December 15, 2025