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PT-141

Bremelanotide, Vyleesi

A synthetic peptide analog of alpha-MSH used to treat hypoactive sexual desire disorder by activating melanocortin receptors to enhance sexual arousal.

Quick Stats
Studies 74
Trials 10
Formula C50H68N14O10
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Completed PHASE2 NCT05709444

A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease

Palatin Technologies, Inc
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT01382719

Bremelanotide in Premenopausal Women With Female Sexual Arousal Disorder and/or Hypoactive Sexual Desire Disorder

Palatin Technologies, Inc
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT03973047

Study to Evaluate Rate of Nausea in Healthy Premenopausal Female Subjects Treated With Single Dose of Bremelanotide Alone or With Zofran

AMAG Pharmaceuticals, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT02338960

2. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder

Palatin Technologies, Inc
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE2 NCT06565611

A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity

Palatin Technologies, Inc
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT00425256

Evaluate the Safety and Efficacy of Bremelanotide in Women With Female Sexual Arousal Disorder (FSAD)

Palatin Technologies, Inc
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE4 NCT06867835

Single Dose of Vyleesi in Lactating Female Subjects to Measure the Concentration of Bremelanotide in Breast Milk

Cosette Pharmaceuticals, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE4 NCT04179734

Role of the Melanocortin-4 Receptor in Hypoactive Sexual Desire Disorder

Imperial College Healthcare NHS Trust
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT02333071

1. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder

Palatin Technologies, Inc
INTERVENTIONAL
Updated Dec 15, 2025