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TB-500

Thymosin Beta-4, TB4, Tβ4

A synthetic peptide that promotes tissue repair, reduces inflammation, and enhances healing by regulating actin polymerization and cell migration.

Quick Stats
Studies 6
Trials 21
Formula C212H350N56O78S
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Terminated PHASE2 NCT00311766

A Phase 2 Study on Effect of Thymosin Beta 4 on Wound Healing in Patients With Epidermolysis Bullosa

RegeneRx Biopharmaceuticals, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT02974907

Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2

ReGenTree, LLC
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn PHASE2 NCT01311518

A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial Infarction

RegeneRx Biopharmaceuticals, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT04555824

A Phase 1a Study of Thymosin Beta 4 in Healthy Volunteers

Beijing Northland Biotech. Co., Ltd.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT00382174

Study of Thymosin Beta 4 in Patients With Pressure Ulcers

RegeneRx Biopharmaceuticals, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT05485818

Safety and Efficacy Study of Thymosin Beta 4 in Patients With Acute Myocardial Infarction.Infarction

Beijing Northland Biotech. Co., Ltd.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT04555850

A Phase 1b Study of Thymosin Beta 4 in Healthy Volunteers

Beijing Northland Biotech. Co., Ltd.
INTERVENTIONAL
Updated Dec 15, 2025
Terminated PHASE2 NCT00598871

A Phase 2 Study of the Safety and Efficacy of Thymosin Beta 4 for Treating Corneal Wounds

ReGenTree, LLC
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT01387347

Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye

ReGenTree, LLC
INTERVENTIONAL
Updated Dec 15, 2025
Terminated PHASE4 NCT01417988

Prevention of Early Mortality by Presumptive Tuberculosis (TB) Treatment

Prof JMA Lange
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE3 NCT05555589

Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

ReGenTree, LLC
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT03937882

Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3

ReGenTree, LLC
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn PHASE1 NCT00743769

A Phase 1 Safety Study of the Intravenous Administration of Thymosin Beta in Healthy Volunteers

RegeneRx Biopharmaceuticals, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Terminated PHASE3 NCT02600429

Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1

ReGenTree, LLC
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT00832091

Study of Thymosin Beta 4 in Patients With Venous Stasis Ulcers

RegeneRx Biopharmaceuticals, Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT05984134

Efficacy and Safety Study of Thymosin Beta 4 in Patients With Acute Myocardial Infarction

Beijing Northland Biotech. Co., Ltd.
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2, PHASE3 NCT02597803

Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1

ReGenTree, LLC
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT01393132

Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye

Michigan Cornea Consultants, PC
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT04745897

Accessibility of the World Health Organization's eTB Catalogue of Recommendations

McMaster University
INTERVENTIONAL
Updated Dec 15, 2025