[Prevention of postoperative complications in diffuse purulent peritonitis in children].
Bushmelev. V A VA; Pozdeev. V V VV; Nikolaev. M V MV
Key Findings
- Local infiltration of 0.01% thymalin solution was part of a multi‑step protocol for diffuse purulent peritonitis
- The thymalin‑enhanced protocol led to significantly fewer postoperative complications in the treated children
- Results were better than a control group that received standard surgery without thymalin
Practical Outcomes
- Thymalin might aid wound healing when applied locally, but the evidence is limited to a specific pediatric surgery setting. For most biohackers, the finding isn’t directly applicable to everyday health or performance goals, and more research is needed before trying it outside a clinical context.
Summary
A small study on 21 kids with severe abdominal infection showed that adding a tiny amount (0.01%) of the peptide thymalin directly to wound edges during surgery, along with a bunch of other steps, cut post‑surgery complications compared to standard care.
Abstract
A complex pathogenetic approach to the prevention of postoperative complications in generalized fibrinopyogenic peritonitis is suggested. It includes a wide operative access, one-stage cleansing with antiseptics and detoxification solutions, ultrasonic cavitation of the abdominal cavity, creation of laparostomy, local infiltration of the wound edges with 0.01% thymalin solution, correction of hemostasis disorders, and increase of the organism's general reactivity. With the use of this complex the results of treatment were significantly improved in 21 children and the number of complications was much less than in the control group of patients subjected to operation.
Study Information
pubmed
1994