The study looked at 28 people with skin sarcoidosis and tested several drugs, including the peptide thymalin. None of the immune‑boosting treatments, like thymalin, helped, and the best result came from mixing steroids with another drug, but the disease came back in about one‑fifth of patients within two years.

Twenty-eight patients with skin sarcoidosis were treated with thymalin, thymogen, levamisole, dimocifon, with due consideration for their immune status. Immunostimulating therapy has failed. Plaquenil, phthivazide and duplex therapy did not result in noticeable improvement either. An individual pattern of mononuclear phagocyte response to various immunoregulators was revealed. The highest sensitivity to human interferon, hydrocortisone, and prospidine was determined in vitro. The highest effect was achieved by a combination of corticosteroids with prospidine, though in 20 percent of cases the disease recurred within 2 years. Since these drugs are not harmless for the body, the major indications for their prescription to patients with skin sarcoidosis (provided there are no direct indications because of other conditions) are the process activity and dissemination, cosmetic defects because of the disease. In case of a local involvement and uneventful course of the process a follow-up is advisable.