[Age features of bioregulatory therapy of dental diseases.].
Pinelis. I S IS; Pinelis. Y I YI; Kuznik. B I BI; Iordanishvili. A K AK; Vasiliev. M A MA
Key Findings
- Thymalin and similar thymic peptides show immunopharmacological activity that may aid healing of oral tissues.
- These peptides have been used clinically in complex treatment protocols for dental diseases in the elderly.
- Peptide bioregulators derived from cartilage (e.g., sigumir, chondrolux) are also discussed for their potential benefits in oral inflammation and trauma.
Practical Outcomes
- For biohackers interested in oral health, thymalin could be considered as an adjunct to conventional dental care, particularly for age‑related inflammation or post‑injury recovery. Start with low, clinically‑tested doses and monitor immune markers or healing speed. More rigorous trials are needed, so treat it as an experimental supplement rather than a proven cure.
Summary
The paper reviews how peptide bioregulators such as thymalin and related thymic peptides can help treat dental and maxillofacial problems, especially in older adults. It highlights their immune‑modulating and protective effects during trauma, inflammation, and other oral tissue issues, suggesting they could be added to comprehensive dental care plans.
Abstract
The article presents data on the use of peptide bioregulators of cell homeostasis and the protective functions of the body in various dental diseases and pathology of organs and tissues of the maxillofacial region. Issues related to the immunopharmacological effect and clinical use of natural and synthetic peptide thymomimetics (thymalin, thymogen, vilon, epithalamin, cortexin) and peptide bioregulators from cartilaginous (sigumir, chondrolux) and other tissues in case of trauma, as well as inflammatory, inflammatory and other pathological processes of tissues of the oral cavity and maxillofacial region. Particular attention is paid to their use in the complex treatment of dental diseases in the elderly.
Study Information
pubmed
2020