[Effects of thymalin on blood coagulation and contents of proinflammatory and anti-inflammatory cytokines in patients with burns].
Kuznik. B I BI; Vitkovskiĭ. Iu A IuA; Budazhabon. G B GB; Sizonenko. V A VA
Key Findings
- Thymalin reduced disseminated intravascular coagulation and normalized fibrinolysis in burn victims.
- The peptide shifted levels of pro‑ and anti‑inflammatory cytokines toward a more balanced state.
- Patients treated with thymalin required about 5 fewer days for the first skin graft and stayed in the hospital 11 days less on average.
Practical Outcomes
- The results suggest thymalin may aid recovery after severe trauma by modulating clotting and inflammation, but the study is limited to acute burn patients and lacks dosage details. For biohackers, the data provide a modest indication of immune‑modulating potential, yet it does not directly translate to everyday longevity or performance protocols without further safety and dosing research.
Summary
In a small study of 32 severe burn patients, giving the peptide thymalin helped clear dangerous blood clotting problems, balanced inflammation signals, and let doctors finish skin grafts about five days sooner while cutting overall hospital time by roughly eleven days.
Abstract
The authors share their experiences with treatment of 32 patients with burns of the III-IV degrees using an immunomodulator Thymalin which promoted liquidation of the syndrome of disseminated intravascular coagulation, normalization of fibrinolysis, influenced the content of pro-inflammatory and anti-inflammatory cytokins. It allowed to shorten the terms of the first autodermoplasty at an average by 5 days and to make staying of burned patients at the hospital 11 days shorter.
Study Information
pubmed
2000