[Effect of thymalin on blood coagulation and fibrinolysis].
Kuznik. B I BI; Budazhapova. D Ts DTs; Zagrebina. L A LA; Morozov. V G VG; Khavinson. V Kh VKh
Key Findings
- Thymalin (2 mg for 5 days) increased fibrinolytic activity after thrombin injection in cats
- Thrombin caused an initial boost in clotting then a secondary hypocoagulation phase
- The peptide’s effect was observed in an animal model, not humans
Practical Outcomes
- The result hints that thymalin might help enhance clot breakdown, but because it’s only an animal study, there’s no clear protocol for people. Biohackers should wait for human data before trying it for blood health or longevity.
Summary
In a small cat study, giving the peptide thymalin (2 mg daily for five days) made the blood break down clots faster after a clot‑forming challenge, compared to cats that didn’t get the peptide. The experiment showed an early spike in clotting followed by a later drop, and thymalin seemed to boost the later clot‑breakdown phase.
Abstract
Experiments were made on 20 cats to show that within the first minutes intravenous administration of thrombin led to the enhancement of blood coagulation, an abrupt lowering in fibrinogen concentration, growth of antithrombin III activity and inhibition of fibrinolysis. 30-60 minutes after thrombin injection there developed a secondary hypocoagulation accompanied by the increment of the level of natural anticoagulants and by drastic enhancement of fibrinolysis. In animals given timalin in a dose of 2 mg for 5 days, the injection of thrombin produced a more remarkable increase in blood fibrinolytic activity.
Study Information
pubmed
1981