PROMOTE: The Effect of a Six Week Prebiotic Supplementation on Wellbeing of Young Adults.
Brief Summary
The study will investigate whether taking a prebiotic for six weeks helps to reduce morning cortisol levels in healthy young adults with mild to moderate stress compared to a placebo. Individuals should continue with their usual lifestyle during the study. Other factors of wellbeing will also be assessed.
Detailed Description
PROMOTE is a double blinded parallel randomised controlled-trial investigating if prebiotic supplementation reduce awakening salivary cortisol response, reported as area under the curve compared to a maltodextrin placebo in healthy young adults with a mild-to-moderate self reported stress score. There will be a focus on biological secondary outcomes to better understand how supplementation may influence the microbiome using metabolomics and sequencing techniques. In addition to other measures of wellbeing captured by questionnaires and activity monitors.
Interventions
Primary Outcomes
Trial Information
NCT06566157
Not Yet Recruiting
INTERVENTIONAL
NA
University of Southampton
December 15, 2025