[The combined therapy of chronic pyoderma taking into account body immunological reactivity and staphylococcal antibiotic resistance].
Rodionov. A N AN; Khavinson. V Kh VKh; Barbinov. V V VV
Key Findings
- Thymogen was given first to improve immune status and make staph bacteria more sensitive to antibiotics
- A second stage added antibiotics plus agents that stimulate phagocytosis and humoral immunity
- The combined approach led to clinical recovery in roughly 74% of cases
Practical Outcomes
- The results suggest thymogen might help the immune system fight stubborn skin infections, but the study is tiny and focused on a specific disease, so it isn’t a ready‑to‑use protocol for general health or longevity.
Summary
A small study of 23 people with long‑lasting skin infections used a synthetic thymus peptide called thymogen to boost the immune system before giving antibiotics, and reported about 74% of patients got better.
Abstract
Summarizing the results of treatment in 23 patients the authors propose an effective two-staged method to treat chronic pyoderma. This method is based on administration of synthetic peptide of thymus--"thymogen", which is used to correct the immune status and increase sensitivity of staphylococci to antibiotics at the zones of cutaneous affection. The second stage of this method consists in administration of antibiotics in combination with stimulators of phagocytosis and humoral immunity. The results prove the high efficiency of thymogen application in complex management of chronic pyoderma: up to 73.9% of clinic recoveries.
Study Information
pubmed
1992