[The biochemical and immunological indices in the rehabilitation period of the victims of the accident on the Komsomolets atomic submarine].
Iakovlev. G M GM; Khavinson. V Kh VKh; Seryĭ. S V SV; Zhukov. V V VV; Neburchilov. V G VG
Key Findings
- Severe cold exposure caused metabolic disruption and immune suppression in the patients.
- Thymogen was used as an immunocorrective treatment during rehabilitation.
- Blood tests showed gradual normalization of metabolic and immune indices after thymogen therapy.
Practical Outcomes
- Thymogen may aid immune recovery after extreme physiological stress, but the data come from a very specific, acute injury setting and lack dosage details, so biohackers should view it as a modest, preliminary hint rather than a ready‑to‑use protocol.
Summary
A study on submarine crew members who suffered severe cold showed that giving them thymogen, a synthetic peptide from the thymus, helped their immune system and metabolism recover during rehab. The patients gradually improved, with blood markers returning toward normal.
Abstract
Biochemical and immunological indexes of peripheral blood were compiled in military sanatorium "Divnomorskoe" in seamen who have suffered from general supercooling in the result of "Komsomolets" atomic submarine breakdown. The patients had the symptoms of metabolic disturbance, immunodepression, a great concentration of proteins in acute phase and activity of MB-fraction of creatine phosphokinase. Immunodepression after the general supercooling was mainly conditioned by oppression of differentiation, metabolic changes and functional activity of T-lymphocytes. A course of immunocorrective therapy was employed using "thymogen"--synthetic peptide of thymus. In the process of rehabilitation there was a gradual functional recovery, normalization of metabolism and immunological indexes.
Study Information
pubmed
1991