[A cytomorphological basis for the correction of radiation-induced immunodeficiencies and hematopoietic depression using thymus and bone marrow peptides].
Khmel'nitskiĭ. O K OK; Grintsevich. I I II; Kotov. V A VA; Seryĭ. S V SV
Key Findings
- Thymogen and related peptides aided recovery of thymus, bone marrow, spleen, and lymph nodes after radiation exposure
- Neutrophil (white blood cell) function improved with peptide treatment
- Patients reported less asthenia (fatigue) following the therapy
Practical Outcomes
- The results suggest thymogen could be explored as an immune‑support supplement after severe stress like radiation, but the study doesn’t provide clear dosing or safety guidance for everyday use, so biohackers should treat it as preliminary evidence rather than a ready‑to‑use protocol.
Summary
A study on 100 patients and 160 animals found that a mix of thymus‑derived peptides, including the synthetic peptide thymogen, helped restore immune function after radiation damage, improving blood cell counts and reducing fatigue.
Abstract
The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied. Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes. Thymalin was able to compensate for immune disturbances and reduce manifestations of asthenia.
Study Information
pubmed
1993