[Possibilities of the application of antioxidants and antihypoxants in a complex therapy of obsessive conditions in different mental disorders].
Podsevatkin. V G VG; Kiriukhina. S V SV
Key Findings
- Patients with OCD or tic disorders showed immune and hormonal dysregulation.
- A combined treatment of mexidol, thymogen, and hyperbaric oxygen was more effective than typical neuroleptic and anxiolytic therapy.
- The study suggests thymogen may have a role in modulating immune/hormonal pathways linked to obsessive conditions.
Practical Outcomes
- For biohackers interested in mental‑health optimization, thymogen could be considered as an adjunct to standard treatments for OCD or tic disorders, but the exact dose and protocol are not detailed. The benefit appears modest and is tied to a multi‑component regimen, so further personal experimentation and caution are advised.
Summary
In a study of 84 people with obsessive‑compulsive disorder or tic disorders, adding the peptide thymogen (along with mexidol and hyperbaric oxygen) helped improve symptoms more than standard drugs like antipsychotics and benzodiazepines. The researchers also noted immune system and hormone imbalances in these patients.
Abstract
Based on the study of 84 patients with a syndrome of persistence within obsessive-compulsive neurosis (OCN) and generalized tic disease (GTD), we found the dysfunction of humoral and cellular immune reactions with the disturbance of regulation of hypophysis-adrenal and hypophysis-thyroid systems. The complex psychopharmacological effect of mexidol, thymogen and hyperbaric oxygenation was significantly higher compared to traditional therapy (neuroleptics and benzodiazepine anxiolytics) applied to patients with OCN and GTD.
Study Information
pubmed
2010