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Tirzepatide

Mounjaro, Zepbound, LY3298176

A dual GLP-1 and GIP receptor agonist used for type 2 diabetes and obesity, enhancing insulin secretion, suppressing glucagon, and promoting weight loss.

Quick Stats
Studies 183
Trials 100
Formula C225H348N48O68
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Active Not Recruiting PHASE3 NCT06588296

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE3 NCT06075667

A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE4 NCT06635057

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT04255433

A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE4 NCT05433584

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting PHASE2 NCT07078838

Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer

UNC Lineberger Comprehensive Cancer Center
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT03311724

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting NA NCT07176663

Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure

Shahid Beheshti University of Medical Sciences
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting PHASE2 NCT06737042

Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants

Gan and Lee Pharmaceuticals, USA
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE1, PHASE2 NCT07000955

Tolerance and Pharmacokinetic/Pharmacokinetic Study of IBI362 15mg in Patients With Moderate to Severe Obesity

Innovent Biologics (Suzhou) Co. Ltd.
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE3 NCT05556512

A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NA NCT06734312

MAINTAIN (Mucosal AblatIoN Therapy After INcretins)

Dr. Christopher McGowan
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting PHASE4 NCT06657209

Normal-weight Diabetes: Adipocyte-directed Therapy with Pioglitazone or Tirzepatide

Stanford University
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NA NCT06431308

Nutritional Therapy to Incretin-based Anti-obesity Medications in the Management of Gastrointestinal Adverse Events

Ariel University
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT04657003

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT07128082

The Long COVID Treatment Trial

Scripps Translational Science Institute
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting PHASE2 NCT06820281

Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes

Garvan Institute of Medical Research
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting NCT07156331

Research on Effects of Drugs on Body Composition and Function With Imaging in Diabetes

Kristin Clemens
OBSERVATIONAL
Updated Dec 15, 2025