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Tirzepatide

Mounjaro, Zepbound, LY3298176

A dual GLP-1 and GIP receptor agonist used for type 2 diabetes and obesity, enhancing insulin secretion, suppressing glucagon, and promoting weight loss.

Quick Stats
Studies 183
Trials 100
Formula C225H348N48O68
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Completed PHASE1 NCT05978713

A Study of Tirzepatide (LY3298176) in Healthy Lactating Females

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE4 NCT05553093

Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 Diabetes

Nanjing First Hospital, Nanjing Medical University
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT04235959

A Study of Tirzepatide in Chinese Participants With Type 2 Diabetes Mellitus

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE4 NCT06803888

Bariatric Surgery vs. Semaglutide vs. Tirzepatide

Ali Aminian
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT06895408

Separate and Combined Extrapancreatic Effects of GIP and GLP-1

University Hospital, Gentofte, Copenhagen
INTERVENTIONAL
Updated Dec 15, 2025
Enrolling By Invitation PHASE2, PHASE3 NCT06162715

GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial

Vanderbilt University Medical Center
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting PHASE1 NCT07095517

Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NCT06790160

Study of Patients Being Treated With Anti-obesity Medication

Texas Tech University
OBSERVATIONAL
Updated Dec 15, 2025
Not Yet Recruiting NCT07251803

GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound

Medical University of South Carolina
OBSERVATIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT06935838

Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV

University of Hawaii
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT06976853

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

Washington University School of Medicine
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting EARLY PHASE1 NCT06759701

Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study

M.D. Anderson Cancer Center
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE4 NCT05564039

A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE4 NCT06374875

Fibrosis Lessens After Metabolic Surgery

Ali Aminian
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE1 NCT05822544

Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes

OrsoBio, Inc
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE3 NCT06246799

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

The University of Texas Health Science Center at San Antonio
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT05691712

A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes

Eli Lilly and Company
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NCT07262762

Spartina® (Tirzepatide) Effectiveness and Safety Evaluation

Cinnagen
OBSERVATIONAL
Updated Dec 15, 2025