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KE, L-Lys-L-Glu, lysylglutamic acid
A synthetic dipeptide that modulates immune function, promotes chromatin remodeling, and exhibits anti-aging effects by enhancing gene expression and immune responses.
Kozina. L S LS
The study found that a few short peptides, including vilon, epitalon, vesugen, and especially pinealon, can help protect cells from low‑oxygen stress in animal experiments. Pinealon worked best, likely by boosting the body's own antioxidant enzymes rather than just blocking harmful free radicals.
Fridman. N V NV; Linkova. N S NS; Polyakova. V O VO; Drobintseva. A O AO; Тrofimova. S V SV; K...
A lab study found that a short peptide called KE (Lys‑Glu, also known as Vilon) can boost two important skin‑cell proteins: collagen I and sirtuin‑6. In old skin cells, the peptide raised collagen levels by about 83%, and it increased sirtuin‑6 by 1.6‑fold in young cells and 2.6‑fold in old cells. This suggests the peptide helps skin cells stay more youthful in a dish, but the work was done in cell cultures, not on real people.
Pliss. G B GB; Mel'nikov. A S AS; Malinin. V V VV; Khavinson. V K VK
In a rat study, a tiny protein called vilon (made of lysine and glutamic acid) lowered the chance of bladder tumors caused by a specific chemical. Treated rats got tumors at a rate of 56% versus 75.5% in untreated rats, and early cancer‑related changes in the bladder lining were cut roughly in half.
Gavrisheva. N A NA; Malinin. V V VV; Ses. T P TP; Kozlov. K L KL; Panchenko. A V AV; Titkov. A Yu AY
In a rat study, giving the peptide Vilon under the skin lowered a harmful protein (TGF‑beta1) in the blood and made tiny gut blood vessels less leaky, but only when the rats were in the early stage of chronic kidney damage.
Lezhava. Teimuraz T; Khavison. Vladimir V; Monaselidze. Jamlet J; Jokhadze. Tinatin T; Dvalishvili....
A lab study found that the synthetic peptide Vilon can loosen certain tightly packed DNA structures in immune cells taken from older people, which may turn on some genes that are usually silent. However, this effect was seen only in cell cultures, not in real humans, and the study didn’t test any doses or health outcomes.
Barykina. O P OP; Iuzhakov. V V VV; Chalisova. N I NI
In a rat study, a synthetic peptide called vilon (and a related compound epigene) was given at a tiny dose and caused more tumor cells to die and slowed tumor growth, suggesting it might one day help treat cancer, but the research is only in animals and not ready for human use.
Xu. Qinming Q; Chen. Hui H; Zhu. Junming J; Li. Xing X; Yang. Jingang J; Deng. Xiaocui X; Yuan. Qing...
Scientists made a tiny carrier using graphene oxide and a special polymer that can hold the chemotherapy drug paclitaxel better and release it faster in acidic environments, like tumors. The carrier itself is not toxic to cells, and when loaded with the drug it kills cancer cells just as well as the drug alone. However, this is a lab‑scale cancer‑treatment technology, not something you can use at home for health or performance improvement.
Kudriavtseva. M V MV; Bezborodkina. N N NN; Sek. E N EN; Shapiro. I Ia IIa; Baranovskiĭ. A Iu...
In a rat study, a tiny daily dose of the dipeptide Vilon was given after the animals had liver damage from a toxin. The drug caused a small rise in one liver enzyme and modest increases in liver cell protein and DNA content, but it didn’t improve sugar storage or other key liver enzymes. The overall effect was weak and only seen in rats, not humans.
Bykov. N M NM; Chalisova. N I NI
The study looked at tiny amounts of a peptide called vilon on rat spleen tissue grown in the lab and found that even extremely low concentrations seemed to change how the tissue grew, especially in older rats, hinting it might one day be useful for anti‑aging treatments, but it’s only an early‑stage animal experiment.
Aleksinskaya. E S ES; Nazarov. S B SB; Posiseeva. L V LV; Nazarova. A O AO; Malyshkina. A I AI
In a rat study, researchers tested surgery, a drug called Vilon, and the two together for treating endometriosis. They found that combining surgery with an injection of Vilon into the abdomen gave the best results for the rats' reproductive health.
Chalisova. N I NI; Khavinson. V Kh VKh; Penniiaĭnen. V A VA; Grigor'ev. E I EI
A lab study tested three thymus‑derived peptides (vilon, thymogen, thymalin) on rat thymus and spleen pieces grown in dishes. The peptides helped tissue from older (21‑day) rats grow, but slowed tissue from newborn (1‑day) rats. Adding a plant protein (concanavalin A) changed the effects, generally reducing its activity.
Kniaz'kin. I V IV; Iuzhakov. V V VV; Chalisova. N I NI; Grigor'ev. E I EI
A lab study showed that a tiny synthetic peptide called vilon (made of lysine and glutamate) helped keep rat spleen tissue stable and encouraged cell regeneration, especially in tissue taken from old rats. This hints it might have anti‑aging potential, but the work was done only in petri dishes with rat organs, not in living humans.
Barykina. O P OP; Iuzhakov. V V VV; Chalisova. N I NI; Kvetnoĭ. I M IM; Konovalov. S S SS
In mouse experiments, a synthetic peptide called vilon helped mice with lung cancer live longer when given alone, but when it was mixed with the chemotherapy drug cyclophosphane, the mice did worse. In lab-grown spleen tissue from rats, vilon caused cell death (apoptosis) in both young and old animals and blocked the harmful effects of cyclophosphane at very low concentrations. The authors suggest that vilon and chemotherapy should not be taken together.
Mathis. C C; Maugars. Y Y; Vilon. P P; Prost. A A
The article describes a rare case where sarcoidosis shows up as severe isolated high calcium in the blood, explains that granuloma cells make too much active vitamin D (1,25‑dihydroxyvitamin D3) which drives the calcium rise, and notes that treatment is usually steroids, sometimes hydroxychloroquine.
Kańduła. Maciej M MM; Aldoshin. Alexander D AD; Singh. Swati S; Kolaczyk. Eric D ED; Kre...
The paper describes ViLoN, a computer algorithm that combines different kinds of molecular data to group patients more accurately, but it doesn’t test any drug or supplement and offers no direct advice you can use.
Maugars. Y Y; Mathis. C C; Vilon. P P; Prost. A A
The study looked at giving corticosteroid shots into the sacroiliac joint of people with a specific arthritis (seronegative spondylarthropathy) and found most patients felt better for several months, but this has little relevance for peptide‑focused biohackers interested in general longevity or performance.
Maugars. Y Y; Clochon. P P; Grardel. B B; Hary. S S; Phélip. X X; Forestier. R R; Gest. D D; Vi...
This study looked at bone health in 33 women with anorexia nervosa, comparing those who had fractures to those who didn’t. It found that most patients had low lumbar bone mineral content, and those with fractures had even lower values, were older, and had longer periods of illness and amenorrhea. The research does not involve the peptide vilon and offers no actionable advice for longevity, metabolic health, or performance optimization.
Zhang. He H; Li. Jingda J; Chen. Amei A; Liu. Qingping Q
The study looks at how a specific protein fragment (beta‑2‑GPI) sticks to oxidized LDL particles in a test‑tube, using lab techniques and computer models. It maps the exact spots where the two molecules bind, but it does not test any health effects or practical uses of the protein.
Bykov. N M NM; Chalisova. N I NI; Zeziulin. P N PN
A lab study looked at how a peptide called vilon affects cell growth in spleen tissue taken from rats of different ages. In a dish, vilon made spleen cells multiply more, both in young and old rats, but the pattern of growth differed between the center and the edges of the tissue.
Vilon. P P; Fiche. M M; Maugars. Y Y; Ducloux. J M JM; Carlier. N N; Poirier. P P; Forest. M M; Pros...
A patient who took a lot of the drug etretinate over many years developed a rare bone cancer in the forearm. While earlier cases of bone growth from etretinate were harmless, this tumor might be related to the drug, but it could also just be a coincidence.