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Tesamorelin

Egrifta, TH9507

A synthetic growth hormone-releasing hormone analog used to reduce excess abdominal fat in HIV-infected patients with lipodystrophy.

Quick Stats
Studies 64
Trials 24
Formula C221H366N72O67S
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Terminated PHASE2 NCT01388920

Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle Wasting

Theratechnologies
INTERVENTIONAL
Updated Dec 15, 2025
Terminated NCT01579695

Long-term Observational Study in HIV Subjects Exposed to EGRIFTA®

Theratechnologies
OBSERVATIONAL
Updated Dec 15, 2025
Completed NCT03826160

Growth Hormone Dynamics and Cardiac Steatosis in HIV

Massachusetts General Hospital
OBSERVATIONAL
Updated Dec 15, 2025
Terminated PHASE4 NCT01591902

Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®

Theratechnologies
INTERVENTIONAL
Updated Dec 15, 2025
Completed NCT05383456

The Visceral Adiposity Measurement and Observation Study

Theratechnologies
OBSERVATIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT03150511

Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury

Johns Hopkins University
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT02572323

Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected Persons

University of California, San Diego
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn PHASE2 NCT02931474

Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia

National Institute of Nursing Research (NINR)
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT00608023

TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy

Theratechnologies
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT01264497

Safety Study of TH9507 in Subjects With Stable, Type 2 Diabetes

Theratechnologies
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT02553603

The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive Impairment

The University of Texas Medical Branch, Galveston
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT00850564

Effect of Short Term Growth Hormone Releasing Hormone in Healthy Men

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT06554717

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT01263717

Effects of Growth Hormone Releasing Hormone in HIV

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT00795210

Effects of Short-term Growth Hormone in HIV-infected Patients

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT00123253

TH9507 in Patients With HIV-Associated Lipodystrophy

Theratechnologies
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT02012556

Pharmacokinetic and Pharmacodynamic Study of TH9507, a Growth Hormone-Releasing Factor Analog, in HIV Positive Patients

Theratechnologies
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn NA NCT01632592

Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone Analogue

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT00257712

SMART: Somatotrophics, Memory, and Aging Research Trial

University of Washington
INTERVENTIONAL
Updated Dec 15, 2025
Completed NA NCT02196831

Tesamorelin Effects on Liver Fat and Histology in HIV

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025