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Thymosin-alpha-1

Thymalfasin, Zadaxin, Thymosin α1

A synthetic 28-amino acid peptide that enhances immune function by modulating T-cell activity, used for viral infections and immunodeficiencies.

Quick Stats
Studies 759
Trials 63
Formula C129H215N33O55
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Unknown PHASE2 NCT02976740

SBRT Combination With rhGM-CSF and Tα1 for Stage IV NSCLC Patients Who Failed in Second-line Chemotherapy

The First Affiliated Hospital of Xiamen University
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT03659578

Study of Thymosin α1 to Reduce Acute Pneumonia For Bulky None-small Cell Lung Cancer

Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting PHASE2 NCT06573398

Radiotherapy With Sequential Chemotherapy Combined With PD-1 Inhibitor and Thymalfasin for BRPC

Ruijin Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT02366208

Phase II Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg Positive Chronic Hepatitis B

Jiangsu Hansoh Pharmaceutical Co., Ltd.
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT06584006

Thymalfasin and Recombinant Human IL-2 Injections in Treating Lymphocytopenia for Patients With Malignant Hematological Tumors

The First Affiliated Hospital of Xiamen University
INTERVENTIONAL
Updated Dec 15, 2025
Unknown PHASE3 NCT02127268

Thymosin-α1 in Cancer-Related Fatigue

Zhigang Zhang
INTERVENTIONAL
Updated Dec 15, 2025
Terminated PHASE2 NCT04487444

Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection

Rhode Island Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NA NCT06598839

Immuno-effect of Tα1 for Stage I NSCLC

Yousheng Mao
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting NCT04901104

Long-term Prognosis of Patients With Sepsis After Immunotherapy

Sun Yat-sen University
OBSERVATIONAL
Updated Dec 15, 2025
Recruiting NA NCT06401447

TPF Concurrent Chemo-radiotherapy Plus Immunotherapy for Local Advanced Esophageal Squamous Cell Carcinoma

Fudan University
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting PHASE2 NCT06056804

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Beijing Friendship Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1, PHASE2 NCT00197860

Dendritic Cell Based Therapy of Renal Cell Carcinoma

Inge Marie Svane
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn PHASE2 NCT02535988

Abscopal Effect for Metastatic Colorectal Cancer

Zhejiang Provincial People's Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Unknown PHASE4 NCT04524169

Immunotherapy for Elderly Patients With Chronic Osteoporotic Pain

RenJi Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE4 NCT02473406

Thymosin Alpha 1 in the Prevention of Pancreatic Infection Following Acute Necrotizing Pancreatitis

Weiqin Li
INTERVENTIONAL
Updated Dec 15, 2025
Unknown PHASE4 NCT05658692

Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome

Second Affiliated Hospital, School of Medicine, Zhejiang University
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1, PHASE2 NCT02646189

Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patients

Replicor Inc.
INTERVENTIONAL
Updated Dec 15, 2025