Thymosin-alpha-1
Thymalfasin, Zadaxin, Thymosin α1
A synthetic 28-amino acid peptide that enhances immune function by modulating T-cell activity, used for viral infections and immunodeficiencies.
Unknown
NCT06024356
Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for Locally Advanced Mid-low Rectal Cancer
Beijing Friendship Hospital
OBSERVATIONAL
Updated Dec 15, 2025
Completed
PHASE3
NCT02867267
The Efficacy and Safety of Ta1 for Sepsis
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting
NA
NCT06607926
Neoadjuvant With Tα1 Plus Immuno-chemotherapy for Resectable NSCLC
Xuanwu Hospital, Beijing
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE2
NCT02233075
REP 2139-Ca / Pegasys™ Combination Therapy in Hepatitis B / Hepatitis D Co-infection
Replicor Inc.
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE2
NCT00911443
Thymosin Alpha 1, Interferon Alpha, or Both, in Combination With Dacarbazine in Patients With Malignant Melanoma
sigma-tau i.f.r. S.p.A.
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
PHASE3
NCT02366247
Phase Ⅲ Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg-positive Chronic Hepatitis B
Jiangsu Hansoh Pharmaceutical Co., Ltd.
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
PHASE2
NCT02906150
Thymosin Alpha 1 Plus Maintenance Therapy With the Standard of Care (SoC) in Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC), EGFR Wild Type
SciClone Pharmaceuticals
INTERVENTIONAL
Updated Dec 15, 2025
Completed
NA
NCT00711620
Efficacy of Thymosin alpha1 for Severe Sepsis
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn
PHASE2
NCT02542930
Abscopal Effect for Metastatic Non-small Cell Lung Cancer.
Zhejiang Provincial People's Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE4
NCT00291616
Efficacy Study of Thymosin alpha1 & Pegylated Interferon-alpha2a to Treat Chronic Hepatitis B
Seoul National University Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting
PHASE2
NCT06829355
"Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer"
Beijing Friendship Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
PHASE2
NCT02787447
Radiotherapy Combined With Thymosin for Metastatic NSCLC Patients Who Showed Stable Disease After First Line TKI Therapy
First People's Hospital of Hangzhou
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE4
NCT01938820
Optimized Treatment and Regression of HBV-induced Early Cirrhosis
Beijing Friendship Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
PHASE2
NCT02545751
SBRT Combined With Thymalfasin for Metastatic Esophageal Cancer
Hangzhou Cancer Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Active Not Recruiting
PHASE2
NCT06139419
The Impact of Thymosin α-1 on the Efficacy of Concurrent Chemoradiotherapy Followed by Immunotherpay Consolidation for Locally Advanced NSCLC
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn
PHASE2
NCT00935558
Dendritic Cell Based Therapy for Breast Cancer Patients
Inge Marie Svane
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting
PHASE2
NCT07103395
A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung Cancer
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE4
NCT02883595
Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting
PHASE1
NCT06821100
Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine
The Methodist Hospital Research Institute
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
PHASE1, PHASE2
NCT00580450
Thymosin Alfa 1 in Recipients of Allogeneic Hematopoietic Transplantation for Hematological Malignancies
University Of Perugia
INTERVENTIONAL
Updated Dec 15, 2025