Thymosin-alpha-1
Thymalfasin, Zadaxin, Thymosin α1
A synthetic 28-amino acid peptide that enhances immune function by modulating T-cell activity, used for viral infections and immunodeficiencies.
Unknown
PHASE2
NCT03663764
Hypofractionated Chemoradiotherapy and Thymosin α1 in Unresectable or Recurrent Thymic Epithelial Tumor
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Completed
EARLY PHASE1
NCT04963712
Zadaxin and HIV-positive Patients With Immune Reconstitution Disorder
Shanghai Public Health Clinical Center
INTERVENTIONAL
Updated Dec 15, 2025
Withdrawn
PHASE2
NCT02542137
Abscopal Effect for Metastatic Small Cell Lung Cancer
Zhejiang Provincial People's Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE3
NCT00040027
Thymosin Plus PEG-Interferon in Non-Cirrhotic Hepatitis C Patients Who Did Not Respond to Interferon or Interferon Plus Ribavirin
SciClone Pharmaceuticals
INTERVENTIONAL
Updated Dec 15, 2025
Completed
NA
NCT03082885
The Efficacy and Safety of Thymosin-α1 in Patients With HBV-related ACLF
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE2
NCT04428008
Thymosin Alpha 1 to Prevent COVID-19 Infection in Renal Dialysis Patients
William B. Ershler, MD
INTERVENTIONAL
Updated Dec 15, 2025
Enrolling By Invitation
NA
NCT06966687
Protective Effect of Ulinastatin and Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA XI)
Nanjing Medical University
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting
PHASE2
NCT07277439
Phase II Trial of Neoadjuvant Thymalfasin, PD-1 Inhibitor, and Chemoradiotherapy for cStage III GEJ Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting
PHASE2
NCT05790447
Thymalfasin-based PRaG Mode for Advanced Refractory Solid Tumors
Second Affiliated Hospital of Soochow University
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
NA
NCT05487469
Thymosin α1 Use in Rheumatic Heart Disease Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass
Nanjing Medical University
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
PHASE3
NCT04320238
Experimental Trial of rhIFNα Nasal Drops to Prevent 2019-nCOV in Medical Staff
Shanghai Jiao Tong University School of Medicine
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE2
NCT01031966
A Pilot Study to Evaluate ZADAXIN's® (Thymalfasin) Ability to Enhance Immune Response to the H1N1sw Influenza Vaccine
sigma-tau i.f.r. S.p.A.
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting
PHASE2
NCT07103408
A Study Evaluating Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade for Limited-stage Small Cell Lung Cancer
Sun Yat-sen University
INTERVENTIONAL
Updated Dec 15, 2025
Completed
NA
NCT03509688
The Curative Effect of Entecavir Combined Resveratrol on HBV patients-a Multi-center, Random, Open Clinical Trial
The First Hospital of Jilin University
INTERVENTIONAL
Updated Dec 15, 2025
Unknown
PHASE4
NCT03448744
Efficacy and Safety of Combination Therapy of Thymalfasin and Entecavir in HBeAg-positive ETV-experienced Patients
Wen-hong Zhang
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting
PHASE3
NCT05086614
Thymosin-alpha 1 for Adjuvant Treatment After Radical Resection of High-risk Stage II and III Colorectal Cancer
Fudan University
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting
PHASE4
NCT06178146
Thymosin Alpha-1 for irAE Secondary to ICIs
Jun Wang
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE3
NCT00039962
Thymosin Plus PEG-Interferon in Hepatitis C Patients With Cirrhosis Who Did Not Respond to Interferon or Interferon Plus Ribavirin
SciClone Pharmaceuticals
INTERVENTIONAL
Updated Dec 15, 2025
Completed
PHASE1
NCT00001036
The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection
National Institute of Allergy and Infectious Diseases (NIAID)
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting
NA
NCT05339529
Protective Effect of Thymosin Α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II)
Nanjing Medical University
INTERVENTIONAL
Updated Dec 15, 2025