Zakutskiĭ. A N AN; Chalisova. N I NI; Ryzhak. G A GA; Aniskina. A I AI; Filippov. S V SV; Zezi...
In a lab study using rat organ pieces, a tiny amount (0.05 ng/ml) of several synthetic peptides, including bronchogen, helped the tissues grow better than untreated samples. The effect was seen in both young and old rats, hinting the peptides might boost tissue repair as we age.
Titova. O N ON; Kuzubova. N A NA; Lebedeva. E S ES; Preobrazhenskaya. T N TN; Surkova. E A EA; Dvora...
In a rat model of COPD, a short four‑amino‑acid peptide called bronchogen lowered lung inflammation, helped the airway lining heal, and boosted local immune proteins and a surfactant that keeps the lungs flexible.
Monaselidze. J R JR; Khavinson. V Kh VKh; Gorgoshidze. M Z MZ; Khachidze. D G DG; Lomidze. E M EM; J...
The study examines ...
Fedoreyeva. L I LI; Dilovarova. T A TA; Ashapkin. V V VV; Martirosyan. Yu Ts YT; Khavinson. V Kh VK;...
The study shows that a tiny peptide called bronchogen can boost growth and leaf formation in tobacco plant cells when used at extremely low doses, likely by tweaking the activity of certain plant genes that control development.
Kuzubova. N A NA; Lebedeva. E S ES; Dvorakovskaya. I V IV; Surkova. E A EA; Platonova. I S IS; Titov...
On the model of chronic obstructive pulmonary disease, the effect of therapy with low-molecular-weight peptides on restructuring and functional activity of bronchial epithelium for restoring the immune and barrier function of the lungs and prevention of inflammatory process progression was studied. Chronic obstructive pulmonary disease was modeled in rats by 60-day intermittent exposure to NO2. Administration of tetrapeptide Bronchogen for 1 month eliminates symptoms of remodeling of the bronchial epithelium and lung tissue typical of chronic obstructive pulmonary disease (goblet cell hyperplasia, squamous metaplasia, lymphocytic infiltration and emphysema, and restoration of ciliated cells). Enhanced production of secretory IgA, a local immunity marker, attested to normalization of functional activity of bronchial epithelium, while normalization of cell composition and profile of proinflammatory cytokines in the bronchoalveolar space reflected reduction of neutrophilic inflammation.
Fedoreyeva. L I LI; Kireev. I I II; Khavinson. V Kh VKh; Vanyushin. B F BF
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Khavinson. V Kh VKh; Linkova. N S NS; Polyakova. V O VO; Kheifets. O V OV; Tarnovskaya. S I SI; Kvet...
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Sugár. István I; Vörös. Attila A; Diczházi. Csaba C; Barabás. Lorá...
The paper reports two rare cases of bronchogenic cysts—abnormal fluid‑filled sacs that develop from airway tissue—found in unusual locations (the chest and the abdomen) and only correctly identified after surgical removal and lab analysis.
Rudas. G G; Kádár. K K
A newborn baby had trouble breathing because of a fluid‑filled cyst in the airway (a bronchogenic cyst). The doctors used an ultrasound scan to spot the cyst, showing that imaging can quickly identify such hidden problems in the chest.
Akos. Molnár Béla MB; Péter. Kaliszky K; Edina. Nagy N; János. Horányi H; E...
A teen girl who was very thin had an ultrasound that showed what looked like an adrenal tumor, but during laparoscopic surgery doctors discovered a 6‑8 cm cyst behind the kidney. The cyst turned out to be a rare retroperitoneal bronchogenic cyst, a type of birth‑defect cyst normally found in the chest, not the abdomen. Microscopic analysis showed it was lined with ciliated airway‑type cells and mucus glands, with no cartilage or gut lining.