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Kisspeptin-10

KP-10, Metastin (45-54), Kisspeptin-10 (human), KiSS-1

Kisspeptin-10 is a decapeptide that activates the KISS1R receptor to stimulate GnRH release, regulating the reproductive hormone axis and fertility.

Quick Stats
Studies 877
Trials 47
Formula C63H83N17O14
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Enrolling By Invitation NCT03877939

Detection of Kisspeptins and miRNAs in Patients With Non-viable Pregnancy

Vida Recoletas Sevilla
OBSERVATIONAL
Updated Dec 15, 2025
Terminated PHASE1 NCT05901467

Recall by Genotype: Neuropeptide Stimulation

Stephanie B. Seminara, MD
INTERVENTIONAL
Updated Dec 15, 2025
Completed NCT01956851

Association of Kisspeptin Levels With Insulin Secretion in Diabetes Mellitus

Ganga Care Hospital, Nagpur
OBSERVATIONAL
Updated Dec 15, 2025
Withdrawn NCT00814437

Physiological Role of KiSS-1/GPR54 System in the Human Ovary

Vida Recoletas Sevilla
OBSERVATIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT05971849

Dampening the Reproductive Axis With Continuous Kisspeptin

Stephanie B. Seminara, MD
INTERVENTIONAL
Updated Dec 15, 2025
Completed NCT04012632

Kisspeptin/GPR54 Pathway and Early Puberty

Shenzhen Center for Disease Control and Prevention
OBSERVATIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT03771326

KP-10 and Insulin Secretion in Men

Quaid-e-Azam University
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NCT06793098

Functional Proteins in Polycystic Ovary Syndrome

Jagiellonian University
OBSERVATIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT03315325

Age-dependent Changes in the Responsiveness of Hypothalamic Pituitary Gonadal Axis in Men

Quaid-e-Azam University
INTERVENTIONAL
Updated Dec 15, 2025
Completed NCT06775990

Molecules Associated with Pediatric Obesity

Istanbul University - Cerrahpasa
OBSERVATIONAL
Updated Dec 15, 2025
Recruiting NA NCT02081924

Reproductive Hormones During Sustained Administration of Kisspeptin

Imperial College London
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE3 NCT02514629

Testosterone, Metformin, or Both, for Hypogonadism in Obese Males

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
INTERVENTIONAL
Updated Dec 15, 2025
Unknown NCT05835089

Evaluation of Some Puberty-related Hormones Among Children and Adolescents With Chronic Kidney Diseases

Sohag University
OBSERVATIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT01438073

Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling

Massachusetts General Hospital
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NCT05971836

The Molecular Basis of Inherited Reproductive Disorders

Stephanie B. Seminara, MD
OBSERVATIONAL
Updated Dec 15, 2025
Completed PHASE2 NCT04648969

Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism

Stephanie B. Seminara, MD
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting PHASE1 NCT07224490

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

Stephanie B. Seminara, MD
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting PHASE2 NCT07182526

Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome

Al-Mustansiriyah University
INTERVENTIONAL
Updated Dec 15, 2025
Completed PHASE1 NCT05633966

Kisspeptin Administration Subcutaneously to Patients With Reproductive Disorders

Stephanie B. Seminara, MD
INTERVENTIONAL
Updated Dec 15, 2025