Menu
Peptide Database
Results
No peptides found
Featured

Use search to browse all 100+ peptides

Thymogen

Glu-Trp, EW dipeptide, Oglufanide, L-Glutamyl-L-tryptophan

A synthetic dipeptide that modulates the immune system by enhancing T-cell differentiation, cytokine production, and overall immune response.

Quick Stats
Studies 94
Trials 51
Formula C16H19N3O5
Clear All
Utility 1
pubmed 2008

[Dynamics of the behavioral response and cortisole level caused by the combined action of mexidole, diazepam, thymogen, and hyperbaric oxygenation in mice under immobilization stress conditions].

Podsevatkin. V G VG; Kiriukhina. S V SV; Podsevatkin. D V DV; Podsevatkina. S V SV; Blinov. D S DS

In stressed mice, a mix of a drug called mexidole, a sedative (diazepam), a peptide called thymogen, and hyperbaric oxygen helped lower anxiety, boost movement and exploration, and bring cortisol levels back to normal. The authors say this works by affecting the immune and hormone systems.

Utility 1
pubmed 2008

[Effects of mercazolyl and L-thyroxine on the antiedematous activity of immunotropic preparations during development of toxic brain edema and swelling].

Platonov. I A IA; Anashchenkova. T A TA; Andreeva. T A TA

In rats, messing with thyroid hormones changes how immune‑boosting peptides like thymogen work against brain swelling. Adding thyroid drugs with thymogen and similar peptides lowered brain water content, but the overall effect was modest and the study was done in a very specific animal model of toxic brain edema.

Utility 1
pubmed 1994

[Cellular immunity in patients with gonorrhea and gonorrhea-chlamydia infection during treatment with pefloxacin in combination with thymogen].

Delektorskiĭ. V V VV; Iashkova. G N GN; Fedorov. S M SM; Sammak. U T UT; Lupan. I N IN; Popova...

The study looked at people with gonorrhea or gonorrhea‑chlamydia infections and gave them the antibiotic pefloxacin together with a peptide called thymogen. They found that adding thymogen seemed to boost the activity of white blood cells that eat bacteria, suggesting a stronger immune response when the two are combined.

Utility 1
pubmed Dec 14, 2004

Angiogenesis inhibitor IM862 is ineffective against AIDS-Kaposi's sarcoma in a phase III trial, but demonstrates sustained, potent effect of highly active antiretroviral therapy: from the AIDS Malignancy Consortium and IM862 Study Team.

Noy. Ariela A; Scadden. David T DT; Lee. Jeannette J; Dezube. Bruce J BJ; Aboulafia. David D; Tulpul...

A large trial found that the synthetic peptide IM862 (a glutamine‑tryptophan dipeptide) does not improve Kaposi's sarcoma outcomes in HIV patients and may even speed disease progression, with no major side effects observed.

Utility 1
pubmed Mar 15, 1999

Reciprocal effect of optical isomerism of EW-dipeptides on immune response.

Deigin. V I VI; Poverenny. A M AM; Semina. O V OV; Semenets. T N TN

Researchers tested two mirror‑image versions of a tiny protein piece (EW dipeptide). The D‑form blocked the growth of blood‑forming cells in mouse bone marrow, while the L‑form helped those cells recover after low‑dose radiation. Adding thymus cells could cancel the D‑form’s blocking effect. The D‑form also stopped stem cells from entering the DNA‑making phase.

Utility 1
pubmed 1994

[The effect of a number of pharmacological preparations on Na-H metabolic activity and on the passive permeability for protons of the sarcolemma of the isolated heart].

Alabovskiĭ. V V VV; Nikolaevskiĭ. V A VA; Reznikov. K M KM; Vinokurova. O V OV; Putilina...

In a lab study on isolated rat hearts, the peptide thymogen did not change the heart cell's sodium‑hydrogen exchange activity or the membrane's passive proton leak. In other words, thymogen showed no direct effect on these cardiac ion‑transport processes.

pubmed 1995

[Treatment with thymogen and myelopid of patients with bronchial asthma].

Zoloedov. V I VI; Zemskov. A M AM; Stupnitskiĭ. A A AA; Goriainova. T A TA

The abstract discusses vitamin E and nicotinamide helping early‑stage type 1 diabetes patients, not thymogen or asthma, so it offers no practical guidance for biohackers interested in the peptide.

pubmed 1996

[The antagonistic properties of bacteria isolated from the digestive tract of female mink housed in the area of the Chernobyl Atomic Electric Power Station].

Sudenko. V I VI; Groma. L I LI; Podgorskiĭ. V S VS

The study looked at gut bacteria from female minks living near Chernobyl and found different types and amounts of bacteria in various gut sections, with younger minks showing stronger antibacterial activity. Some minks were given the peptide thymogen, which seemed to boost the antibacterial properties of certain Enterococcus strains, but the research was done in animals, not people.

pubmed 1998

[Bile duct decompression and immune correction in the surgical treatment of mechanical jaundice of non-tumor origin].

Shabunin. A V AV; Tarabrin. V I VI; Malyshev. I Iu IIu

The study examined how long to decompress bile ducts before major surgery in patients with non‑cancerous jaundice, finding that short‑term decompression (up to 5 days) quickly normalizes liver function, while longer jaundice (up to 15 days) needs extra immune‑support before surgery. It doesn’t involve thymogen or any supplement you can take at home.

pubmed 2012

[Experimental justification of approaches to pharmacological correction of delayed disorders caused by acute ethylene glycol poisoning].

Liubishin. M M MM; Sivak. K V KV; Savateeva-Liubimova. T N TN

In rats that were poisoned with ethylene glycol, researchers found that giving immune‑boosting drugs together with the usual ethanol antidote helped the kidneys and immune system recover, but this finding is specific to a toxic poisoning scenario and doesn’t translate to everyday health or longevity practices.

pubmed Aug 1, 2000

Antiangiogenic treatment enhances photodynamic therapy responsiveness in a mouse mammary carcinoma.

Ferrario. A A; von Tiehl. K F KF; Rucker. N N; Schwarz. M A MA; Gill. P S PS; Gomer. C J CJ

In mice with breast cancer, a light‑based treatment called photodynamic therapy (PDT) caused the tumors to become low in oxygen and produce more VEGF, a factor that helps blood vessels grow. Adding drugs that block new blood‑vessel formation (anti‑angiogenic agents) made the PDT work better and lowered VEGF levels. The study was done in mice and did not involve the peptide thymogen.

pubmed 1998

[A comparative study of conservative treatment schemes in chronic tonsillitis in children].

Khmel'nitskaia. N M NM; Vorob'ev. K V KV; Kliachko. L L LL; Ankhimova. E S ES; Kosenko. V A VA; Tyrn...

The study looked at three non‑surgical treatments for kids with chronic tonsillitis and found that a plant‑based tincture (Chelidonium majus) seemed to boost throat function, immune markers, and cut down how often the tonsillitis came back. It does not mention thymogen or any peptide‑related effects.

pubmed 2001

Clinical aspects and management of AIDS-related Kaposi's sarcoma.

Levine. A M AM; Tulpule. A A

This abstract talks about Kaposi's sarcoma in people with AIDS, its causes, and how it’s treated with chemotherapy, local therapies, and HIV drugs. It does not mention the peptide thymogen or give any guidance that biohackers could use.