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Thymalin

Thymulin, Thymic Factor, Serum Thymic Factor, Facteur Thymique Serique

A synthetic thymic nonapeptide that modulates immune function by promoting T-cell differentiation and enhancing overall immunity.

Quick Stats
Studies 202
Trials 37
Formula C33H54N12O15
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Utility 1
pubmed 1990

Application of thymic factor "Thymalin" in complex treatment of endometrial cancer patients.

Bakhidze. E V EV

A study gave the peptide thymalin to 35 women with endometrial cancer who were also getting hormone therapy and surgery. The researchers saw some improvement in immune cell numbers and a few tissue‑level changes, but the work was limited to cancer patients and didn’t show how thymalin could be used for general health or performance.

Utility 1
pubmed 1990

[Use of thymic peptide thymalin in the complex treatment of therapy-resistant schizophrenia].

Govorin. N V NV; Stupina. O P OP

A study gave a thymus‑derived peptide called thymalin together with standard antipsychotic drugs to 36 people whose schizophrenia didn’t respond to usual treatment and who also had immune system problems. The combo helped many patients feel better, become more active, and have fewer drug side‑effects, and these improvements matched a return toward normal immune markers.

Utility 1
pubmed 1989

[The dynamics of thymalin localization in human thymus cells in embryogenesis].

Khlystova. Z S ZS; Kalinina. I I II; Khavinson. V Kh VKh

The study simply shows that the peptide thymalin naturally appears in the thymus of human embryos and young children, being found in various parts of the gland as it develops. It doesn’t test any health effects or give dosing advice, so it’s mainly a basic science observation.

Utility 1
pubmed 1989

[The efficacy of using thymalin in diabetes mellitus in children].

Kurbanov. T G TG; Kal'bieva. B M BM; Zakieva. G G GG

A small study looked at giving the peptide thymalin to kids with diabetes and said it helped their blood‑sugar‑related health measures, but it doesn’t give any details on how much was used or how it was given.

Utility 1
pubmed 1990

[Homeostatic effect of thymalin in multiple sclerosis].

Akimov. G A GA; Golovkin. V I VI; Khavinson. V Kh VKh

The study examined how a myelin‑related peptide called thymalin interacts with hormone tests in people with multiple sclerosis and suggests that pairing it with arginine‑vasopressin might help balance the immune, endocrine, and nervous systems and possibly prevent disease flare‑ups.

Utility 1
pubmed 1993

[Evaluation of the state of systemic and local cellular immunity using loading tests].

Stefani. A V AV; Mikhu. I Ia IIa; Khavkin. A I AI

The study looked at how a peptide called thymalin changes immune cells in the blood and gut of kids with stomach and intestine problems. They found three different ways the T‑cells reacted and created numbers to describe those reactions, but the work was done in a lab setting on sick children, not healthy adults.

Utility 1
pubmed 1992

[The treatment of meningococcemia by preserving immune homeostasis].

Lutsik. B D BD

The study looked at how the immune system changes in people with severe meningococcal infection and shock, and suggested a mix of drugs—including a peptide called thymalin—to help regulate immunity. The authors say doses should be personalized and monitored with immune tests, but the work is focused on treating a life‑threatening infection, not everyday health or longevity.

Utility 1
pubmed 1991

[The clinico-pathogenetic significance of general and local defense and injury factors in endometritis after cesarean section].

Vdovichenko. Iu P IuP

The study looked at women who got a C‑section and found that changes in the uterus’s immune defenses happen before they show signs of infection. Adding the peptide thymalin along with an antibiotic inside the uterus seemed to help prevent the infection, but the findings are specific to post‑surgery patients.

Utility 1
pubmed 1991

[The characteristics of the reaction of lymphocyte blast transformation using different mitogens in patients with chronic hepatitis].

Lukash. N V NV; Krutikov. S N SN; Ludan. V V VV; Brusilovskiĭ. A I AI

The study looked at how a peptide called thymalin affects immune cells in people with chronic hepatitis compared to healthy volunteers. It found that patients with the disease showed early signs of weaker immune cell activity, which could be spotted using a lab test called cytometry. The research doesn’t give clear guidance on using thymalin for health‑boosting in healthy people.

Utility 1
pubmed 1992

[The effect of therapy with cytostatics and immunomodulators on mitotic pathology in Lewis tumor cells in mice].

Potapov. Iu N IuN; Krutova. T V TV; Pashkova. V S VS; Khaleev. D V DV

A mouse experiment tested the peptide thymalin alongside chemotherapy drugs and found it changes how tumor cells divide, increasing some abnormal cell divisions. This suggests thymalin can affect chemotherapy effects, but the study is early‑stage, done in mice, and doesn’t give clear guidance for human use.

Utility 1
pubmed 1992

[Immunomodulation in dystrophic diseases of the joints].

Delevskiĭ. Iu P IuP; Isaeva. E G EG

The study looked at 357 people with joint problems and found many immune system issues, suggesting they might need drugs that adjust immunity. Thymalin was listed as one of several possible agents, but the paper doesn’t give clear dosing or direct benefits for healthy people or performance goals.

Utility 1
pubmed 1991

Age-dependent experimental tumor dissemination of murine melanoma B16.

Baumgart. J J; Zippel. D D

In a mouse study, older mice got many more lung tumors than young ones. Giving a strong immune‑suppressing drug made tumors even worse, while a viral‑mimic drug helped reduce them. The peptide thymalin didn’t change tumor spread at all, suggesting it isn’t useful for fighting cancer in this model.

Utility 1
pubmed 1990

[The treatment of women with dyshormonal myocardiodystrophy].

Iakimenko-Vasiutina. E A EA

A study used a cold‑based therapy together with the peptide thymalin on women with a rare heart‑muscle disorder linked to hormonal issues and uterine growths. The combination appeared to improve heart‑related symptoms and boost immune system markers, but the research is very specific and doesn’t give clear dosing or broader health advice.