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KP-10, Metastin (45-54), Kisspeptin-10 (human), KiSS-1
Kisspeptin-10 is a decapeptide that activates the KISS1R receptor to stimulate GnRH release, regulating the reproductive hormone axis and fertility.
Sousa. Josane F JF; Espreafico. Enilza M EM
This study just compared gene activity in early‑stage versus metastatic melanoma cells and noted that the early cells have the metastasis‑suppressing gene KISS1 turned on, but it doesn’t test kisspeptin‑10 as a treatment or give any health‑related advice.
Dittmer. Angela A; Schunke. Dario D; Dittmer. Jürgen J
Scientists discovered that the protein kisspeptin (KISS-1) and a related hormone (PTHrP) can change how breast cancer cells clump together in lab dishes, but this finding is about cancer cell behavior and does not translate into any health‑oriented advice for everyday people.
Ruppen. Isabel I; Grau. Laura L; Orenes-Piñero. Esteban E; Ashman. Keith K; Gil. Marta M; Algab...
The paper examined how putting the KiSS-1 gene (which can suppress cancer spread) into bladder cancer cells changes the proteins those cells make. It identified many proteins that shift when KiSS-1 is present and highlighted Filamin A as a possible marker of tumor progression. The work is basic cancer research and does not give any direct advice or protocols for health‑optimizing practices.
Schwarting. Gerald A GA; Wierman. Margaret E ME; Tobet. Stuart A SA
The paper explains how brain cells that make a hormone called GnRH, which controls reproduction, develop in the nose area and travel to the brain. If they don’t reach the right spot, it can cause infertility or loss of smell, and scientists are still figuring out the exact signals that guide this journey.
Prentice. Leah M LM; Klausen. Christian C; Kalloger. Steve S; Köbel. Martin M; McKinney. Steven...
The study looked at ovarian cancer tissue and found that tumors with high levels of the proteins kisspeptin and its receptor GPR54 were linked to better survival rates, especially in a specific clear‑cell type of ovarian cancer. These proteins act as markers that doctors might use to predict how a patient will do, but they aren't something you can take or change yourself.
Zhou. Xiyou X; Weatherford. Eric T ET; Liu. Xuebo X; Born. Ella E; Keen. Henry L HL; Sigmund. Curt D...
The study looks at how deleting DNA upstream of the human renin gene in mice affects renin production, showing that large deletions cause big changes in renin levels but keep nearby genes working normally. It’s a basic genetics experiment and doesn’t give any tips or data that biohackers could use for health, longevity, or performance.
Parent. Anne-Simone AS; Matagne. Valerie V; Westphal. Manfred M; Heger. Sabine S; Ojeda. Sergio S; J...
The study looked at brain lesions that sometimes cause early puberty and found that a few specific genes are more active in those lesions. It does not test kisspeptin‑10 or give any tips on how to use it for health or performance.
Martins. C M O CM; Fernandes. B F BF; Antecka. E E; Di Cesare. S S; Mansure. J J C JJ; Marshall. J-C...
Researchers looked at a gene called KISS1, which can suppress cancer spread, in eye melanoma tumors. They found that most tumors had KISS1 protein, but lower levels were linked to a higher chance of the cancer spreading. The gene and its receptor were also present in melanoma cell lines.
Dhar. Dipok Kumar DK; Naora. Hiroyuki H; Kubota. Hirofumi H; Maruyama. Riruke R; Yoshimura. Hiroshi...
The study found that low levels of the KiSS-1 gene in stomach cancer are linked to more aggressive tumors and poorer survival, suggesting KiSS-1 might help stop cancer spread, but it doesn’t give any direct advice for health hacks or everyday use.
Mitchell. D C DC; Stafford. L J LJ; Li. D D; Bar-Eli. M M; Liu. M M
Scientists found that a protein called DRIP-130 helps turn on the KiSS-1 gene, which can stop cancer cells from spreading. When DRIP-130 is missing, KiSS-1 is turned off and melanoma cells become more invasive. Adding back DRIP-130 and another protein, Sp1, restores KiSS-1 and reduces the cells' ability to move and invade.
Farina. Antonio A; Sekizawa. Akihiko A; Purwosunu. Yuditiya Y; Rizzo. Nicola N; Banzola. Irina I; Co...
Researchers measured several mRNA molecules in the blood of pregnant women and found that most of them, including the KISS-1 gene (which makes kisspeptin), change in women who develop preeclampsia, a pregnancy complication. The study is about detecting the disease early, not about using kisspeptin as a supplement or therapy for health or performance.
Bilban. Martin M; Ghaffari-Tabrizi. Nassim N; Hintermann. Edith E; Bauer. Sandra S; Molzer. Sylvia S...
Researchers found that a tiny protein called kisspeptin-10, which is naturally made by early pregnancy cells, can slow down those cells' ability to move and invade tissue, without affecting how fast they grow. This effect seems to be linked to changes in calcium inside the cells and reduced activity of enzymes that break down surrounding material.
Lippincott. Margaret F MF; León. Silvia S; Chan. Yee-Ming YM; Fergani. Chrysanthi C; Talbi. Raj...
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Corno. Cristina C; Perego. Paola P
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Amorim. Paulo V G H PVGH; Grande. Isabella P P IPP; Batista. Rafael L RL; Silveira. Leticia F G LFG;...
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Wang. Xiao-Qing XQ; Fang. Pei-Fei PF; Zhang. Cheng C; Xu. Ya-Yun YY; Song. Xian-Bing XB; Liang. Jun...
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Nistala. Ravi R; Zhang. Xiaoji X; Sigmund. Curt D CD
The study shows that when a big chunk of human DNA containing the KISS1 gene (which makes kisspeptin), the REN gene, and another nearby gene is inserted into mice, each gene still behaves mostly like it does in humans, keeping its own tissue‑specific activity. This is a basic science finding about gene regulation, not about using kisspeptin‑10 as a supplement or therapy.
West. A A; Vojta. P J PJ; Welch. D R DR; Weissman. B E BE
This study just maps where the KISS1 gene sits in our DNA and shows its basic layout, but it doesn’t give any tips on how to use kisspeptin-10 for health or performance.
Hiden. Ursula U; Bilban. Martin M; Knöfler. Martin M; Desoye. Gernot G
The study shows that kisspeptin-10, a small protein made by the placenta, can block the invasion of certain placental cells that are important for pregnancy development. This effect is strongest early in pregnancy and appears to help keep the invasion process tightly controlled.
Song. Guo-Qing GQ; Zhao. Yi Y
Researchers found that a short piece of the hormone kisspeptin, called kisspeptin‑10, can slow down the sugar‑burning style that many breast cancer cells use to grow, and it does this by turning on a cell‑signaling pathway called Smad. This effect was seen in breast cancer cells in a dish and in mouse tumors, but the study didn’t look at healthy people or give any dosing advice.